Giant Centrifugal and Necrotizing Cutaneous Metastases of Melanoma: A Brief Review of the Literature and a Case Report

J Cutan Med Surg. 2016 May;20(3):252-4. doi: 10.1177/1203475415620395. Epub 2015 Dec 1.

Abstract

Background: Melanoma is a neoplasm derived from melanocytes of the skin and other sites. In the natural history of melanoma, cutaneous metastases occur relatively frequently and can arise in early or late stages of the disease.

Objective and methods: Melanoma skin metastases have a variable appearance. Several clinical appearances are described in the literature.

Results and conclusion: We describe an unusual clinical pattern of cutaneous melanoma metastasis, defined as giant, centrifugal, and necrotizing, and we provide a brief review of the literature.

Keywords: cancer; dermatology; melanoma.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Brain Neoplasms / secondary*
  • Fatal Outcome
  • Humans
  • Liver Neoplasms / secondary*
  • Lung Neoplasms / secondary*
  • Male
  • Melanoma / complications
  • Melanoma / secondary*
  • Necrosis / etiology
  • Skin / pathology*
  • Skin Neoplasms / complications
  • Skin Neoplasms / pathology*
  • Skin Neoplasms / secondary*