Oncologic outcomes after nipple-sparing mastectomy: A single-institution experience

J Surg Oncol. 2016 Jan;113(1):8-11. doi: 10.1002/jso.24097. Epub 2015 Dec 2.

Abstract

Introduction: Long-term oncologic outcomes in nipple-sparing mastectomy (NSM) continue to be defined. Rates of locoregional recurrence for skin-sparing mastectomy (SSM) and NSM in the literature range from 0% to 14.3%. We investigated the outcomes of NSM at our institution.

Methods: Patients undergoing NSM at our institution from 2006 to 2014 were identified and outcomes were analyzed.

Results: From 2006 to 2014, 319 patients (555 breasts) underwent NSM. One-hundered and fourty-one patients (237 breasts) had long-term follow-up available. Average patient age and BMI were 47.78 and 24.63. Eighty-four percent of patients underwent mastectomy primarily for a therapeutic indication. Average tumor size was 1.50 cm with the most common histologic type being invasive ductal carcinoma (62.7%) followed by DCIS (23.7%). Average patient follow-up was 30.73 months. There was one (0.8%) incidence of ipsilateral chest-wall recurrence. There were 0.37 complications per patient.

Conclusions: We examined our institutional outcomes with NSM and found a locoregional recurrence rate of 0.8% with no nipple-areolar complex recurrence. This rate is lower than published rates for both NSM and SSM.

Keywords: breast cancer; locoregional recurrence; nipple-sparing mastectomy; oncologic; outcomes; reconstructive.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Body Mass Index
  • Breast Neoplasms / pathology
  • Breast Neoplasms / surgery*
  • Carcinoma, Ductal, Breast / surgery
  • Carcinoma, Intraductal, Noninfiltrating / surgery
  • Female
  • Humans
  • Mammaplasty / adverse effects
  • Mastectomy / methods*
  • Middle Aged
  • Neoplasm Recurrence, Local / epidemiology
  • Neoplasm Recurrence, Local / prevention & control
  • Neoplasm Staging
  • New York / epidemiology
  • Nipples*
  • Quality of Life
  • Treatment Outcome