[Surveillance of Plasmodium falciparum drug sensitivity in Yaounde and its surroundings (Cameroon). In vivo and in vitro study]

Bull Soc Pathol Exot Filiales. 1989;82(2):217-23.
[Article in French]

Abstract

Among 172 strains collected in Yaoundé 60% are chloroquine-resistant, 37% are amodiaquine-resistant, instead of quinine and mefloquine which are completely efficient. Among 30 strains collected at a rural health center (where self treatment decreases), 27% are chloroquine-resistant. New therapeutic schemes for first and second line treatment in endemic areas must be evaluated.

Publication types

  • English Abstract

MeSH terms

  • Adolescent
  • Adult
  • Amodiaquine / pharmacology
  • Animals
  • Antimalarials / pharmacology
  • Antimalarials / therapeutic use*
  • Cameroon
  • Child
  • Child, Preschool
  • Chloroquine / pharmacology
  • Humans
  • In Vitro Techniques
  • Infant
  • Malaria / drug therapy*
  • Mefloquine
  • Microbial Sensitivity Tests
  • Middle Aged
  • Plasmodium falciparum / drug effects*
  • Quinine / pharmacology
  • Quinolines / pharmacology
  • Rural Population

Substances

  • Antimalarials
  • Quinolines
  • Amodiaquine
  • Chloroquine
  • Quinine
  • Mefloquine