[Lipemia and bilirubin influences for twenty-four biochemical parameters measurement]

Ann Biol Clin (Paris). 2015 Nov-Dec;73(6):671-89. doi: 10.1684/abc.2015.1088.
[Article in French]

Abstract

The study of the influence of the lipemia and icterus was performed experimentally for twenty-four biochemistry parameters on the Roche Cobas 6000 CE analyzer. Overloads in Intralipid(®) or ditaurate of bilirubin were performed on several plasma pools. The limit of 10% was chosen to define interference on the measurement. The parameters studied were classified into different categories depending on their measurement is affected or not. Knowledge of these data allows the biologist to adapt its reporting procedures in the case of lactescent and/or icteric samples.

Keywords: bilirubin; icterus; interference; lactescence; lipemia.

Publication types

  • English Abstract

MeSH terms

  • Bilirubin / blood*
  • Biomarkers / analysis
  • Biomarkers / blood*
  • Blood Chemical Analysis* / methods
  • Blood Chemical Analysis* / standards
  • Emulsions / pharmacology
  • False Positive Reactions
  • Humans
  • Hyperlipidemias / blood*
  • Hyperlipidemias / complications
  • Jaundice / blood*
  • Jaundice / complications
  • Phospholipids / pharmacology
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Soybean Oil / pharmacology

Substances

  • Biomarkers
  • Emulsions
  • Phospholipids
  • soybean oil, phospholipid emulsion
  • Soybean Oil
  • Bilirubin