Celebrating DNA's Repair Crew

Cell. 2015 Dec 3;163(6):1301-3. doi: 10.1016/j.cell.2015.11.028.

Abstract

This year, the Nobel Prize in Chemistry has been awarded to Tomas Lindahl, Aziz Sancar, and Paul Modrich for their seminal studies of the mechanisms by which cells from bacteria to man repair DNA damage that is generated by normal cellular metabolism and stress from the environment. These studies beautifully illustrate the remarkable power of DNA repair to influence life from evolution through disease susceptibility.

Publication types

  • Biography
  • Historical Article

MeSH terms

  • Bacteria / metabolism
  • Chemistry / history*
  • DNA / chemistry
  • DNA Damage
  • DNA Repair*
  • Eukaryota / metabolism
  • History, 21st Century
  • Humans
  • Nobel Prize*

Substances

  • DNA

Personal name as subject

  • Tomas Lindahl
  • Aziz Sancar
  • Paul Modrich