Acquired Epidermodysplasia Verruciformis Associated with Human Papilloma Virus Type 14 in a Small Bowel Transplanted Child--A Case Report

Pediatr Dermatol. 2016 Jan-Feb;33(1):e1-5. doi: 10.1111/pde.12734. Epub 2015 Dec 8.

Abstract

A 3-year-old African American girl taking sirolimus and tacrolimus for a small bowel transplantation presented with hypopigmented macules and papules throughout her trunk. A biopsy diagnosed epidermodysplasia verruciformis (EV) that was found to be associated with human papillomavirus (HPV) type 14 according to polymerase chain reaction analysis. There are few cases of acquired EV in the setting of organ transplantation. Although there is no standardized treatment for acquired EV, prevention and surveillance for transformation to squamous cell carcinoma are primary concerns.

Publication types

  • Case Reports

MeSH terms

  • Child, Preschool
  • Epidermodysplasia Verruciformis / diagnosis
  • Epidermodysplasia Verruciformis / virology*
  • Female
  • Humans
  • Intestine, Small / transplantation*
  • Organ Transplantation / adverse effects*
  • Papillomaviridae / isolation & purification*
  • Papillomavirus Infections / diagnosis
  • Papillomavirus Infections / virology*
  • Polymerase Chain Reaction
  • Skin / pathology