1 Department of Anesthesia and Intensive Care San Raffaele Scientific Institute Milan, ItalyDivision of Cardiac Anesthesia and Intensive Care, Azienda Ospedaliera Dei Colli, V Monaldi, Naples, ItalyAnesthesia and Critical Care Medicine, Città della Salute e della Scienza Hospital, University of Turin, Turin, ItalyDepartment of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, ItalyDepartment of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, ItalyDepartment of Intensive Care, Austin Hospital, University of Melbourne, Melbourne, Australia.