An Introduction to Genome Annotation

Michael S Campbell; Mark Yandell

doi:10.1002/0471250953.bi0401s52

An Introduction to Genome Annotation

Curr Protoc Bioinformatics. 2015 Dec 17:52:4.1.1-4.1.17. doi: 10.1002/0471250953.bi0401s52.

Authors

Michael S Campbell¹, Mark Yandell^{1

2}

Affiliations

¹ Eccles Institute of Human Genetics, University of Utah, Salt Lake City, Utah.
² USTAR Center for Genetic Discovery, University of Utah, Salt Lake City, Utah.

PMID: 26678385
DOI: 10.1002/0471250953.bi0401s52

Abstract

Genome projects have evolved from large international undertakings to tractable endeavors for a single lab. Accurate genome annotation is critical for successful genomic, genetic, and molecular biology experiments. These annotations can be generated using a number of approaches and available software tools. This unit describes methods for genome annotation and a number of software tools commonly used in gene annotation.

Publication types

Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Data Curation
Exome / genetics
Genome*
Molecular Sequence Annotation / methods*
Quality Control
Sequence Alignment