Multimodal Versus Patient-Controlled Analgesia After an Anterior Cervical Decompression and Fusion

Spine (Phila Pa 1976). 2016 Jun;41(12):994-998. doi: 10.1097/BRS.0000000000001380.

Abstract

Study design: Retrospective analysis of a prospectively maintained surgical registry.

Objective: To compare postoperative narcotic consumption between multimodal analgesia (MMA) and patient-controlled analgesia (PCA) after an anterior cervical discectomy and fusion (ACDF).

Summary of background data: Studies suggest that a multimodal approach to pain management leads to decreased pain and morphine consumption after total joint arthroplasty and lumbar spinal procedures. Patients and surgeons would benefit from knowing whether a multimodal approach to pain management is superior to PCA for ACDF.

Methods: A retrospective cohort study of ACDF patients receiving either MMA or PCA was conducted. Inpatient narcotic consumption, pain scores, nausea/vomiting, hospital length of stay, and narcotic dependence during the months after surgery were compared between MMA and PCA.

Results: A total of 239 patients met inclusion criteria. Of these, 55 (23.0%) received MMA and 184 (77.0%) received PCA. Patients who received MMA had a lower rate of inpatient narcotic consumption (2.5 OME/h vs. 5.8 OME/h, P < 0.001) were less likely to experience nausea/vomiting during the hospitalization (5.5% vs. 37.5%, P < 0.001), and had a shorter hospital length of stay (27.3 vs. 40.1 h, P < 0.001). However, there was no difference between groups in mean visual analogue pain scale during postoperative day zero (4.7 for MMA vs. 5.2 for PCA, P = 0.126) or during postoperative day one (4.1 for MMA vs. 4.1 for PCA, P = 0.937). In addition, there was no difference in the rate of narcotic dependence at the first (P = 0.626) or second (P = 0.480) postoperative visits.

Conclusion: These data suggest that MMA results in lower narcotic consumption than PCA after an ACDF. This difference is associated with a shorter inpatient stay and a decrease in postoperative nausea/vomiting. Critically, MMA and PCA appear to provide similar postoperative analgesia.

Level of evidence: 3.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Analgesia, Patient-Controlled / methods*
  • Analgesia, Patient-Controlled / standards
  • Analgesics, Opioid / administration & dosage
  • Cervical Vertebrae / surgery*
  • Combined Modality Therapy / methods
  • Combined Modality Therapy / standards
  • Decompression, Surgical / adverse effects*
  • Diskectomy / adverse effects
  • Female
  • Humans
  • Male
  • Middle Aged
  • Pain Management / methods*
  • Pain Management / standards
  • Pain, Postoperative / diagnosis
  • Pain, Postoperative / prevention & control*
  • Prospective Studies
  • Registries
  • Retrospective Studies
  • Spinal Fusion / adverse effects*

Substances

  • Analgesics, Opioid