Behavior Test Relevant to α2/α3Na(+)/K(+)-ATPase Gene Modified Mouse Models

Toke Jost Isaksen; Thomas Hellesøe Holm; Karin Lykke-Hartmann

doi:10.1007/978-1-4939-3179-8_30

Behavior Test Relevant to α2/α3Na(+)/K(+)-ATPase Gene Modified Mouse Models

Methods Mol Biol. 2016:1377:341-51. doi: 10.1007/978-1-4939-3179-8_30.

Authors

Toke Jost Isaksen¹, Thomas Hellesøe Holm¹, Karin Lykke-Hartmann^{2

3

4}

Affiliations

¹ Department of Biomedicine and Centre for Membrane Pumps in Cells and Disease-PUMPKIN, Danish National Research Foundation, Aarhus University, Aarhus C, Denmark.
² Department of Biomedicine and Centre for Membrane Pumps in Cells and Disease-PUMPKIN, Danish National Research Foundation, Aarhus University, Aarhus C, Denmark. [email protected].
³ Department of Molecular Biology and Genetics, Aarhus University, Aarhus C, Denmark. [email protected].
⁴ Aarhus Institute of Advanced Studies (AIAS), Aarhus University, Aarhus C, Denmark. [email protected].

PMID: 26695045
DOI: 10.1007/978-1-4939-3179-8_30

Abstract

The behavioral phenotypes of mice are the result of a complex interplay between overall health, sensory abilities, learning and memory, motor function as well as developmental milestones, feeding, sexual, parental, and social behaviors. This chapter lists a selected number of key behavioral tests, specifically designed to assay fundamental behavioral features such as memory, activity, and motor skills in mice models.

Keywords: Animal behavior; Balance beam; Barnes Maze; Grip strength; Mouse model; Open field; Passive avoidance.

MeSH terms

Animals
Avoidance Learning
Behavior, Animal*
Female
Hand Strength
Male
Maze Learning
Mice
Sodium-Potassium-Exchanging ATPase / genetics*

Substances

Sodium-Potassium-Exchanging ATPase