Draft Genome Sequences of a Unique t324-ST541-V Methicillin-Resistant Staphylococcus aureus Strain from a Pig

J Microbiol Biotechnol. 2016 Apr 28;26(4):799-805. doi: 10.4014/jmb.1509.09015.

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA), the major causative agent of nosocomial infection, has also been reported from non-human sources. A sequence type (ST) 541 MRSA isolate designated K12PJN53 was isolated from a healthy pig in 2012. The genome of K12PJN53 consists of 44 contiguous sequences (contigs), totalling 2,880,108 bases with 32.88% GC content. Among the annotated contigs, 14, 17, and 18 contained genes related to antimicrobial resistance, adherence, and toxin genes, respectively. The genomic distance of strain K12PJN53 was close to the ST398 strains. This is the first report of the draft genome sequence of a novel livestock-associated MRSA ST541 strain.

Keywords: Genomics; MRSA; Pig.

MeSH terms

  • Animals
  • Anti-Bacterial Agents / pharmacology
  • Bacterial Adhesion / genetics
  • Bacterial Toxins / genetics
  • Base Sequence
  • Drug Resistance, Bacterial / genetics
  • Genome, Bacterial*
  • Genomics
  • Methicillin-Resistant Staphylococcus aureus / genetics*
  • Methicillin-Resistant Staphylococcus aureus / isolation & purification*
  • Methicillin-Resistant Staphylococcus aureus / physiology
  • Sequence Analysis, DNA*
  • Swine / microbiology*

Substances

  • Anti-Bacterial Agents
  • Bacterial Toxins