Comparison of Targeted Next-Generation and Sanger Sequencing for the BRCA1 and BRCA2 Mutation Screening

Ann Lab Med. 2016 Mar;36(2):197-201. doi: 10.3343/alm.2016.36.2.197.

Authors

Joonhong Park^{1

2}, Woori Jang^{2

3}, Hyojin Chae^{1

2}, Yonggoo Kim^{1

2}, Hyun Young Chi⁴, Myungshin Kim^{1

5}

Affiliations

¹ Department of Laboratory Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.
² Catholic Genetic Laboratory Center, College of Medicine, The Catholic University of Korea, Seoul, Korea.
³ Samkwang Medical Laboratories, Seoul, Korea.
⁴ Samkwang Medical Laboratories, Seoul, Korea. [email protected].
⁵ Catholic Genetic Laboratory Center, College of Medicine, The Catholic University of Korea, Seoul, Korea. [email protected].

No abstract available

Publication types

Comparative Study
Letter
Research Support, Non-U.S. Gov't

MeSH terms

BRCA1 Protein / genetics*
BRCA2 Protein / genetics*
Base Sequence
DNA / chemistry
Databases, Genetic
Female
Hereditary Breast and Ovarian Cancer Syndrome / genetics
High-Throughput Nucleotide Sequencing
Humans
Polymorphism, Single Nucleotide
Sequence Analysis, DNA

Substances

BRCA1 Protein
BRCA1 protein, human
BRCA2 Protein
BRCA2 protein, human
DNA