Presentation of parathyroid adenoma with genu valgum and thoracic deformities

J Pak Med Assoc. 2016 Jan;66(1):101-3.

Abstract

Parathyroid adenoma is the main cause of primary hyperparathyroidism. It is usually asymptomatic and occurs more commonly in adults. It presents with raised parathormone (PTH) and Ca+ levels in serum. Its presentation in adolescence is rare. We report one such incidence of a 14 years old girl who presented with bone pains short stature, and generalized muscle wasting. She was found to have genu valgum at the knee joint, pectus carniatum, scoliosis and cystic changes in pelvis and calvarium. Biochemical investigations and parathyroid Tc-99mMIBI scan confirmed the diagnosis of a parathyroid adenoma. The gland was removed by parathyroidectomy. Till date 12 such cases are reported and none had thoracic, vertebral or calvarium involvement.

Keywords: Endocrinology, Pediatrics, Orthopedics, Parathyroid Adenoma, Radiology..

Publication types

  • Case Reports

MeSH terms

  • Adenoma / complications
  • Adenoma / diagnostic imaging*
  • Adenoma / surgery
  • Adolescent
  • Female
  • Genu Valgum / diagnostic imaging*
  • Genu Valgum / etiology
  • Humans
  • Hypercalcemia / blood
  • Hypercalcemia / diagnosis
  • Hypercalcemia / etiology
  • Hyperparathyroidism, Primary / blood
  • Hyperparathyroidism, Primary / complications
  • Hyperparathyroidism, Primary / diagnosis*
  • Hyperparathyroidism, Primary / surgery
  • Parathyroid Hormone / blood
  • Parathyroid Neoplasms / complications
  • Parathyroid Neoplasms / diagnostic imaging*
  • Parathyroid Neoplasms / surgery
  • Parathyroidectomy
  • Pectus Carinatum / diagnostic imaging*
  • Pectus Carinatum / etiology
  • Pelvic Bones / diagnostic imaging
  • Radiography
  • Radiopharmaceuticals
  • Scoliosis / diagnostic imaging*
  • Scoliosis / etiology
  • Skull / diagnostic imaging
  • Technetium Tc 99m Sestamibi

Substances

  • Parathyroid Hormone
  • Radiopharmaceuticals
  • Technetium Tc 99m Sestamibi