Cytological features of choricarcinoma in a Pap smear: A case report and literature review

Xiaowei Chen; Jason D Wright; Rosanna G Abellar; Anne Koehne de Gonzalez; Nikosa Collins; Thomas C Wright; Diane Hamele-Bena

doi:10.1002/dc.23417

Cytological features of choricarcinoma in a Pap smear: A case report and literature review

Diagn Cytopathol. 2016 Apr;44(4):324-8. doi: 10.1002/dc.23417. Epub 2015 Dec 29.

Authors

Xiaowei Chen¹, Jason D Wright², Rosanna G Abellar¹, Anne Koehne de Gonzalez¹, Nikosa Collins¹, Thomas C Wright¹, Diane Hamele-Bena¹

Affiliations

¹ Department of Pathology and Cell Biology, Columbia University Medical Center, New York, New York.
² Department of Obstetrics and Gynecology, Division of Gynecology Oncology, Columbia University Medical Center, New York, New York.

PMID: 26712464
DOI: 10.1002/dc.23417

Abstract

Choriocarcinoma is an aggressive malignant trophoblastic tumor that mostly occurs during reproductive years. Cytological features of choriocarcinoma in gynecologic Pap smears have not been described. Herein, we report a case of choriocarcinoma in a Pap smear of a patient who had a history of choriocarcinoma with metastatic disease.

Keywords: Pap smear; choriocarcinoma; cytology.

Publication types

Case Reports

MeSH terms

Adult
Antineoplastic Combined Chemotherapy Protocols
Choriocarcinoma / diagnosis*
Choriocarcinoma / drug therapy
Choriocarcinoma / pathology
Choriocarcinoma / surgery
Eye Neoplasms / diagnosis*
Eye Neoplasms / drug therapy
Eye Neoplasms / secondary
Eye Neoplasms / surgery
Female
Gestational Trophoblastic Disease / diagnosis*
Gestational Trophoblastic Disease / drug therapy
Gestational Trophoblastic Disease / pathology
Gestational Trophoblastic Disease / surgery
Humans
Lung Neoplasms / diagnosis*
Lung Neoplasms / drug therapy
Lung Neoplasms / secondary
Lung Neoplasms / surgery
Papanicolaou Test
Pregnancy
Vaginal Smears