1 Division of Critical Care Medicine, Department of Anesthesia, Perioperative, and Pain Medicine; and Department of Neurology, Boston Children's Hospital; and Departments of Anaesthesia and Neurology, Harvard Medical School, Boston, MA Division of Critical Care Medicine, Department of Anesthesia, Perioperative, and Pain Medicine, Boston Children's Hospital; and Departments of Anaesthesia and Pediatrics, Harvard Medical School, Boston, MA.