Morphological analysis and feature extraction of neurons from mouse cortices multiscale 3D microscopic images

Alexis Zubiolo; Kawssar Harb; Michele Studer; Eric Debreuve; Xavier Descombes

doi:10.1109/EMBC.2015.7320118

Morphological analysis and feature extraction of neurons from mouse cortices multiscale 3D microscopic images

Annu Int Conf IEEE Eng Med Biol Soc. 2015:2015:7466-9. doi: 10.1109/EMBC.2015.7320118.

Authors

Alexis Zubiolo, Kawssar Harb, Michele Studer, Eric Debreuve, Xavier Descombes

PMID: 26738018
DOI: 10.1109/EMBC.2015.7320118

Abstract

In this paper, we propose a framework to analyze the morphology of mouse neurons in the layer V of the cortex from 3D microscopic images. We are given 8 sets of images, each of which is composed of a 10x image showing the whole neurons, and a few (2 to 5) 40x images focusing on the somas. The framework consists in segmenting the neurons on both types of images to compute a set of specific morphological features, and in matching the neurons in the 40x images to their counterparts in the 10x images to combine the features we obtained, in a fully automatic fashion.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Algorithms*
Animals
Cerebral Cortex / cytology*
Imaging, Three-Dimensional / methods*
Mice
Neurons / physiology*
Programming, Linear