1 School of Chemistry and Chemical Engineering, Chongqing University, Chongqing 400030, China. [email protected].
2 School of Chemistry and Chemical Engineering, Chongqing University, Chongqing 400030, China. [email protected] and State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, China.
We have developed a one-pot iron-catalysed sequential reaction of secondary amines with primary alcohols, trimethylsilyl cyanide and TBHP under mild reaction conditions to give the corresponding α-aminonitriles.