Zika fever imported from Thailand to Japan, and diagnosed by PCR in the urines

Koh Shinohara; Satoshi Kutsuna; Tomohiko Takasaki; Meng Ling Moi; Makiko Ikeda; Akira Kotaki; Kei Yamamoto; Yoshihiro Fujiya; Momoko Mawatari; Nozomi Takeshita; Kayoko Hayakawa; Shuzo Kanagawa; Yasuyuki Kato; Norio Ohmagari

doi:10.1093/jtm/tav011

Zika fever imported from Thailand to Japan, and diagnosed by PCR in the urines

J Travel Med. 2016 Jan 18;23(1):tav011. doi: 10.1093/jtm/tav011. Print 2016 Jan.

Affiliations

¹ Disease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan and.
² Disease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan and [email protected].
³ Department of Virology, National Institute of Infectious Diseases, Shinjuku-ku, Tokyo, Japan.

PMID: 26782128
DOI: 10.1093/jtm/tav011

Abstract

In July 2014, a Japanese traveller returning from Thailand was investigated for fever, headache, rash and conjunctivitis. Zika virus RNA was detected in his urine sample by real-time reverse transcription polymerase chain reaction. Serological tests showed cross reactivity of IgM against the dengue virus. Zika fever could be misdiagnosed or missed and should be considered in febrile patients with a rash, especially those returning from Thailand.

Keywords: Flaviviridae; Mosquito-borne disease; Zika fever.

Publication types

Case Reports
Review

MeSH terms

Adult
Dengue Virus
Exanthema / virology
Fever / virology
Humans
Immunoglobulin M / blood*
Japan
Male
RNA, Viral / urine*
Real-Time Polymerase Chain Reaction
Thailand
Travel*
Zika Virus / isolation & purification
Zika Virus Infection / diagnosis*

Substances

Immunoglobulin M
RNA, Viral