Oral manifestations in Kindler syndrome: case report and discussion of literature findings

Spec Care Dentist. 2016 Jul;36(4):223-30. doi: 10.1111/scd.12165. Epub 2016 Jan 27.

Abstract

Kindler syndrome is a rare genetic disorder showing some predominant clinical manifestations, for example, trauma-induced blisters, progressive poikiloderma, skin atrophy, and photosensitivity. Oral manifestations are not commonly described and can be often misdiagnosed. This report describes the case of a female patient diagnosed with Kindler syndrome showing the classical clinical features affecting the skin, in addition to oral lesions manifesting as keratotic plaques and ulcers affecting the buccal mucosa, floor of the mouth, alveolar ridge, hard palate, and soft palate. An incisional biopsy was performed to confirm the diagnostic hypothesis of an autoimmune lesion possibly related with the syndrome. Knowledge about the possible manifestations of the Kindler syndrome is important to improve its management.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Blister / complications*
  • Epidermolysis Bullosa / complications*
  • Female
  • Humans
  • Middle Aged
  • Mouth Diseases / etiology*
  • Periodontal Diseases / complications*
  • Photosensitivity Disorders / complications*

Supplementary concepts

  • Poikiloderma of Kindler