Humoral Immunity in Bronchiectasis: Finding Good's Syndrome

Case Rep Pulmonol. 2015:2015:531731. doi: 10.1155/2015/531731. Epub 2015 Dec 29.

Abstract

We present a case of a 37-year-old man with a past history of a surgically removed thymoma, who presented with recurrent pulmonary infections and bronchiectasis. On further testing, he was found to have low total immunoglobulin levels, a constellation of findings known as Good's syndrome. He responded well to immunoglobulin replacement, in addition to the usual treatments for bronchiectasis. We present this case to emphasize the association of bronchiectasis, low immunoglobulins, and thymomas and the role of immunoglobulin replacement as a treatment option.