Addressing inherited predisposition for breast cancer in transplant recipients

J Surg Oncol. 2016 May;113(6):605-8. doi: 10.1002/jso.24193. Epub 2016 Feb 10.

Abstract

Consideration of prophylactic mastectomy surgery following transplantation requires complex medical decision-making, and bias against elective surgery exists because of concern for post-operative complications. Prevention of cancer in transplant recipients is of utmost importance, given the risks of treating malignancy in an immunosuppressed patient. We present a patient case and review of the literature to support a thorough pre-transplantation evaluation of family history and consideration of prophylactic interventions to safeguard the quality of life of transplant recipients. J. Surg. Oncol. 2016;113:605-608. © 2016 Wiley Periodicals, Inc.

Keywords: BRCA1; breast cancer risk; organ transplant; prophylactic mastectomy.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Breast Implantation
  • Cystic Fibrosis / complications
  • Cystic Fibrosis / surgery*
  • Female
  • Hereditary Breast and Ovarian Cancer Syndrome / complications
  • Hereditary Breast and Ovarian Cancer Syndrome / diagnosis
  • Hereditary Breast and Ovarian Cancer Syndrome / genetics
  • Hereditary Breast and Ovarian Cancer Syndrome / prevention & control*
  • Humans
  • Lung Transplantation*
  • Mastectomy, Subcutaneous*