Crystal structure of 3-benzyl-1-[(1,2,3,4-tetra-hydro-naphthalen-1-yl-idene)amino]-thio-urea

Shaaban K Mohamed; Joel T Mague; Mehmet Akkurt; Alaa A Hassan; Ahmed T Abdel-Aziz; Mustafa R Albayati

doi:10.1107/S2056989015021064

Crystal structure of 3-benzyl-1-[(1,2,3,4-tetra-hydro-naphthalen-1-yl-idene)amino]-thio-urea

Acta Crystallogr E Crystallogr Commun. 2015 Nov 21;71(Pt 12):o974-5. doi: 10.1107/S2056989015021064. eCollection 2015 Dec 1.

Authors

Shaaban K Mohamed¹, Joel T Mague², Mehmet Akkurt³, Alaa A Hassan⁴, Ahmed T Abdel-Aziz⁴, Mustafa R Albayati⁵

Affiliations

¹ Faculty of Science & Engineering, School of Healthcare Science, Manchester Metropolitan University, Manchester M1 5GD, England; Chemistry Department, Faculty of Science, Minia University, 61519 El-Minia, Egypt.
² Department of Chemistry, Tulane University, New Orleans, LA 70118, USA.
³ Department of Physics, Faculty of Sciences, Erciyes University, 38039 Kayseri, Turkey.
⁴ Chemistry Department, Faculty of Science, Minia University, 61519 El-Minia, Egypt.
⁵ Kirkuk University, College of Education, Department of Chemistry, Kirkuk, Iraq.

Abstract

In the title compound, C18H19N3S, the dihedral angle between the planes of the benzene rings is 58.63 (8)°. The six-membered ring bonded to the thio-semicarbazide group (r.m.s. deviation = 0.038 Å) adopts a sofa conformation, with one of the methyl-ene-group C atoms as the flap. A short intra-molecular N-H⋯N contact is observed. In the crystal, mol-ecules are linked by weak N-H⋯S inter-actions to generate C(4) chains propagating in the [010] direction, with adjacent mol-ecules related by glide symmetry.

Keywords: antiproliferative agents; crystal structure; thiosemicarabazides.