Controllable layer-by-layer assembly of PVA and phenylboronic acid-derivatized chitosan

Carbohydr Polym. 2016 Apr 20:140:228-32. doi: 10.1016/j.carbpol.2015.12.032. Epub 2015 Dec 17.

Abstract

Phenylboronic acid-derivatized chitosan (chitosan-PBA) were prepared by grafting small molecules bearing phenylboronic acid groups onto chitosan with N-hydroxysuccinimide (NHS) and N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride (EDC) as a coupling reagent pair. Self-assembly multilayer thin films of chitosan-PBA and poly(vinyl alcohol) were subsequently produced under pH control on supporting surfaces, either a silicon wafer or polystyrene latex particles. The driving force of the self-assembly was the ester formation of phenylboronic acid containing polymers with PVA, which can be "turned off" by simple pH control.

Keywords: Amphoteric polyelectrolyte; Chitosan; Layer-by-layer assembly; PVA; Phenylboronic acid.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adhesives / chemistry
  • Boronic Acids / chemistry*
  • Carbodiimides / chemistry
  • Chitosan / chemistry*
  • Hydrogen-Ion Concentration
  • Latex / chemistry
  • Methylamines / chemistry
  • Models, Molecular
  • Molecular Conformation
  • Polystyrenes / chemistry
  • Polyvinyl Alcohol / chemistry*
  • Silicon / chemistry
  • Succinimides / chemistry
  • Surface Properties

Substances

  • 1-(3-dimethylaminopropyl)-dimethylaminopropyl-ethylcarbodiimide hydrochloride
  • Adhesives
  • Boronic Acids
  • Carbodiimides
  • Latex
  • Methylamines
  • Polystyrenes
  • Succinimides
  • Polyvinyl Alcohol
  • Chitosan
  • benzeneboronic acid
  • N-hydroxysuccinimide
  • Silicon