Alpha-synuclein gene variants may predict neurostimulation outcome

Daniel Weiss; Sonja Herrmann; Lisa Wang; Claudia Schulte; Kathrin Brockmann; Christian Plewnia; Thomas Gasser; Manu Sharma; Alireza Gharabaghi; Rejko Krüger

doi:10.1002/mds.26558

Alpha-synuclein gene variants may predict neurostimulation outcome

Mov Disord. 2016 Apr;31(4):601-3. doi: 10.1002/mds.26558. Epub 2016 Feb 16.

Authors

Daniel Weiss^{1

2

3}, Sonja Herrmann^{1

2

3}, Lisa Wang⁴, Claudia Schulte^{1

2}, Kathrin Brockmann^{1

2}, Christian Plewnia^{3

5}, Thomas Gasser^{1

2}, Manu Sharma^{1

4}, Alireza Gharabaghi^{3

6}, Rejko Krüger^{1

2

3

7

8}

Affiliations

¹ Department for Neurodegenerative Diseases and Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.
² German Centre of Neurodegenerative Diseases (DZNE), Tübingen, Germany.
³ Werner Reichardt Centre for Integrative Neuroscience, Tübingen, Germany.
⁴ Centre for Genetic Epidemiology, Institute for Clinical Epidemiology and Applied Biostatistics, University of Tübingen, Tübingen, Germany.
⁵ Department of Psychiatry and Psychotherapy, University of Tübingen, Tübingen, Germany.
⁶ Division of Functional and Restorative Neurosurgery, University of Tübingen, Tübingen, Germany.
⁷ Clinical and Experimental Neuroscience, Luxembourg Center for Systems Biomedicine, University of Luxembourg, Luxembourg City, Luxembourg.
⁸ Centre Hospitalier de Luxembourg, Luxembourg City, Luxembourg.

PMID: 26880248
DOI: 10.1002/mds.26558

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Aged
Deep Brain Stimulation / methods*
Female
Humans
Male
Middle Aged
Outcome Assessment, Health Care*
Parkinson Disease / genetics*
Parkinson Disease / therapy*
Subthalamic Nucleus*
alpha-Synuclein / genetics*

Substances

SNCA protein, human
alpha-Synuclein