Periapical Bone Healing after Apicectomy with and without Retrograde Root Filling with Mineral Trioxide Aggregate: A 6-year Follow-up of a Randomized Controlled Trial

J Endod. 2016 Apr;42(4):533-7. doi: 10.1016/j.joen.2016.01.011. Epub 2016 Feb 19.

Abstract

Introduction: In cases of post-treatment periapical disease, retreatment may be necessary. To choose the most appropriate retreatment method, knowledge of the long-term prognosis is important. Surgical endodontic retreatment (SER) is a relevant treatment method. This study assessed changes in outcome from 1 to 6 years after surgery.

Methods: SER was performed on teeth randomly allocated to have a MTA root-end filling (MTA group) or smoothing of the orthograde gutta-percha filling after apicectomy (GP group). Patients participating in the 1-year follow-up were reinvited for a 6-year clinical and radiographic examination. Three observers assessed treatment outcome both clinically and radiographically from the 1-year and 6-year follow-up examination.

Results: At the 6-year follow-up, 39 of 52 teeth were available and examined (75% participation rate). In the MTA group, 16 of 19 teeth (86%) and in the GP group 11 of 20 teeth (55%) were assessed as successful (P = .04). In the MTA group and the GP group, 80% and 90%, respectively, of teeth assessed as successful at the 1-year follow-up remained successful. All unsuccessful teeth in the MTA group (3 teeth) were lost because of vertical root fracture.

Conclusions: The proportion of healed cases was larger in the MTA group than in the GP group at both the 1-year and 6-year follow-up. Findings indicate that a 1-year follow-up may not be sufficient in assessing the long-term outcome of surgical endodontic retreatment. With a longer follow-up, other factors not directly related to the endodontic treatment may be relevant for a successful outcome. This needs further investigation in larger patient samples.

Keywords: Mineral trioxide aggregate; periapical surgery; radiographic; surgical endodontic retreatment; trioxide aggregate.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Aluminum Compounds / therapeutic use*
  • Apicoectomy / adverse effects
  • Apicoectomy / methods*
  • Bone Regeneration / drug effects*
  • Calcium Compounds / therapeutic use*
  • Drug Combinations
  • Female
  • Gutta-Percha / therapeutic use
  • Humans
  • Male
  • Middle Aged
  • Oxides / therapeutic use*
  • Retreatment
  • Root Canal Filling Materials / therapeutic use*
  • Root Canal Obturation / adverse effects
  • Root Canal Obturation / methods*
  • Root Canal Preparation / methods
  • Silicates / therapeutic use*
  • Treatment Outcome
  • Wound Healing / drug effects*

Substances

  • Aluminum Compounds
  • Calcium Compounds
  • Drug Combinations
  • Oxides
  • Root Canal Filling Materials
  • Silicates
  • mineral trioxide aggregate
  • Gutta-Percha