Abstract
Anaerobiospirillum succiniciproducens is a rare but potentially lethal pathogen. We report a case of A. succiniciproducens bloodstream infection in a 55-year-old man hospitalized for pelvic trauma. The strain was identified by 16sRNA sequencing after several failures of identification by MALDI-TOF MS. The strain was susceptible to beta-lactam antibiotics and ciprofloxacin, but resistant to macrolides and clindamycin. Identification tools must be improved to enhance our knowledge on this rare pathogen and to define optimal therapy.
Keywords:
16s rRNA sequencing; Anaerobiospirillum succiniciproducens; Bacteraemia; Gram-negative anaerobic; Rod-shaped bacteria.
Copyright © 2016 Elsevier Ltd. All rights reserved.
MeSH terms
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Anaerobiospirillum / classification
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Anaerobiospirillum / genetics
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Anaerobiospirillum / isolation & purification*
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Anti-Bacterial Agents / therapeutic use
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Ciprofloxacin / therapeutic use
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Clindamycin / therapeutic use
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Delayed Diagnosis
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Drug Resistance, Bacterial
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Gram-Negative Bacterial Infections / diagnosis*
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Gram-Negative Bacterial Infections / drug therapy
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Gram-Negative Bacterial Infections / microbiology*
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Gram-Negative Bacterial Infections / pathology
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Humans
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Male
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Microbial Sensitivity Tests
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Middle Aged
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Pelvis / injuries
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RNA, Ribosomal, 16S / genetics*
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Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
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beta-Lactams / therapeutic use
Substances
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Anti-Bacterial Agents
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RNA, Ribosomal, 16S
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beta-Lactams
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Clindamycin
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Ciprofloxacin