Comparative Analysis of Proliferation and Viability of Multipotent Mesenchymal Stromal Cells in 3D Scaffolds with Different Architectonics

Bull Exp Biol Med. 2016 Feb;160(4):535-41. doi: 10.1007/s10517-016-3214-8. Epub 2016 Feb 22.

Abstract

3D biodegradable materials (scaffolds) containing bioactive hydroxyapatite molecules fabricated by foaming in supercritical carbon dioxide and by selective laser sintering were used for culturing of mesenchymal stromal cells from the human adipose tissue. Experiments showed that stromal cells from the human adipose tissue adhered and proliferated on all studied types of structures. Addition of hyproxyapatite to the scaffold stimulated proliferation of stromal adipose tissue cells.

Keywords: 3D scaffolds; biodegradable polymers; mesenchymal stromal cells.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adipose Tissue / cytology*
  • Biocompatible Materials*
  • Cell Adhesion
  • Cell Culture Techniques*
  • Cell Differentiation
  • Cell Proliferation
  • Cell Survival
  • Cells, Cultured
  • Durapatite / pharmacology*
  • Humans
  • Mesenchymal Stem Cells / cytology*
  • Tissue Engineering
  • Tissue Scaffolds*

Substances

  • Biocompatible Materials
  • Durapatite