Human Milk for Ill and Medically Compromised Infants: Strategies and Ongoing Innovation

JPEN J Parenter Enteral Nutr. 2016 Aug;40(6):768-82. doi: 10.1177/0148607116629676. Epub 2016 Feb 22.

Abstract

The use of human milk (mother's own milk and/or donor milk) in ill or medically compromised infants frequently requires some adaptation to address medical diagnoses and/or altered nutrition requirements. This tutorial describes the nutrition and immunological benefits of breast milk as well as provides evidence for the use of donor milk when mother's own milk is unavailable. Several strategies used to modify human milk to meet the medical and nutrition needs of an ill or medically compromised infant are reviewed. These strategies include (1) the standard fortification of human milk to support adequate growth, (2) the novel concept of target fortification in preterm infants, (3) instructions on how to alter maternal diet to address cow's milk protein intolerance and/or allergy in breast milk-fed infants, and (4) the removal and modification of the fat in breast milk used in infants diagnosed with chylothorax.

Keywords: breast milk; human milk; infant; nutrition.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cattle
  • Food Hypersensitivity
  • Food, Fortified
  • Humans
  • Immunity
  • Infant
  • Infant Nutritional Physiological Phenomena*
  • Infant, Newborn
  • Infant, Newborn, Diseases / therapy
  • Infant, Premature / growth & development
  • Milk Proteins / immunology
  • Milk, Human* / chemistry
  • Nutritional Requirements
  • Nutritive Value
  • Tissue Donors

Substances

  • Milk Proteins

Grants and funding