Evidence-based guidelines: Improving AGREEment on consistence evaluation

Bruno Vincenzi; Andrea Napolitano; Daniele Santini; Evaristo Maiello; Valter Torri; Giuseppe Tonini

doi:10.1016/j.jbo.2012.04.001

Evidence-based guidelines: Improving AGREEment on consistence evaluation

J Bone Oncol. 2012 Apr 30;1(1):30-4. doi: 10.1016/j.jbo.2012.04.001. eCollection 2012 Jun.

Authors

Bruno Vincenzi¹, Andrea Napolitano¹, Daniele Santini¹, Evaristo Maiello², Valter Torri³, Giuseppe Tonini¹

Affiliations

¹ University Campus Bio-Medico, Department of Medical Oncology, Rome, Italy.
² Istituto di ricovero e cura a carattere scientifico (IRCCS) Casa Sollievo della Sofferenza, San Giovanni Rotondo, Medical Oncology Unit, Foggia, Italy.
³ Mario Negri Institute for Pharmacological Research, Milan, Italy.

Abstract

Modern clinical practice relies on evidence-based medicine (EBM) and evidence-based guidelines (EBGs). The critical evaluation of EBGs value is therefore an essential step to further improve clinical practice. In our opinion, correlating levels of evidence and grades of recommendation can be an easy tool to quickly display internal consistence of EBGs.

Keywords: AGREE; Bone metastasis; EBG; EBM; Guideline.