Chemical Constituents of Plants from the Genus Ixora

Chem Biodivers. 2016 Mar;13(3):275-283. doi: 10.1002/cbdv.201500065.

Abstract

Ixora is a genus of ca. 400 species in the family Rubiaceae. Since the 1940s, eighty-one compounds including phenolics, peptides, terpenoids, and sterols have been isolated from six species of the genus Ixora. Pharmacological studies have shown that these compounds and extracts from the Ixora genus have extensive activities, such as antitumor, chemoprotective, and antioxidant activities. In this review, we summarize the phytochemical progress and list the compounds isolated from the genus Ixora. The biological activities of this genus are also covered.

Keywords: Biological activity; Ixora; Peptides; Phenolics; Terpenoids.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Antineoplastic Agents, Phytogenic / chemistry
  • Antineoplastic Agents, Phytogenic / isolation & purification
  • Antineoplastic Agents, Phytogenic / pharmacology*
  • Antioxidants / chemistry
  • Antioxidants / isolation & purification
  • Antioxidants / pharmacology*
  • Humans
  • Neoplasms / drug therapy
  • Neoplasms / pathology
  • Peptides / chemistry
  • Peptides / isolation & purification
  • Peptides / pharmacology
  • Phenols / chemistry
  • Phenols / isolation & purification
  • Phenols / pharmacology
  • Plant Extracts / chemistry*
  • Plant Extracts / isolation & purification
  • Plant Extracts / pharmacology*
  • Rubiaceae / chemistry*
  • Sterols / chemistry
  • Sterols / isolation & purification
  • Sterols / pharmacology
  • Terpenes / chemistry
  • Terpenes / isolation & purification
  • Terpenes / pharmacology

Substances

  • Antineoplastic Agents, Phytogenic
  • Antioxidants
  • Peptides
  • Phenols
  • Plant Extracts
  • Sterols
  • Terpenes