Targeting constitutively active androgen receptor splice variants in castration resistant prostate cancer

Expert Opin Ther Targets. 2016 Aug;20(8):903-6. doi: 10.1517/14728222.2016.1159676. Epub 2016 Mar 21.
No abstract available

Keywords: Androgen receptor; drug resistance; prostate cancer; splice variants.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Antineoplastic Agents / pharmacology*
  • Biomarkers, Tumor
  • Drug Delivery Systems
  • Gene Expression Regulation, Neoplastic / drug effects*
  • Humans
  • Male
  • Molecular Targeted Therapy
  • Orchiectomy*
  • Prostatic Neoplasms / therapy*
  • Protein Isoforms / genetics
  • Protein Isoforms / metabolism*
  • Receptors, Androgen / genetics
  • Receptors, Androgen / metabolism*

Substances

  • Antineoplastic Agents
  • Biomarkers, Tumor
  • Protein Isoforms
  • Receptors, Androgen