Terbinafine-induced lichenoid drug eruption

Cutan Ocul Toxicol. 2017 Mar;36(1):101-103. doi: 10.3109/15569527.2016.1160101. Epub 2016 Mar 30.

Abstract

Drug-induced lichen planus has been induced by antibiotics, anticonvulsants, antidiabetics, antimalarials, antitubercular drugs, antihypertensives, psychiatric drugs, chemotherapeutic agents, diuretic, heavy metals, NSAIDs, etc. Terbinafine, an antifungal agent, is widely used for dermatophyte infections and onychomycosis. Cutaneous adverse effects of terbinafine are rarely reported. Here, we report a case of terbinafine-induced lichenoid drug eruption in a 22-year-old who presented with generalized lichenoid eruption 2 weeks after terbinafine initiation of. The body and lip cleared completely after 8 weeks of drug withdrawal; nail change cleared after 12 weeks.

Keywords: Drug adverse; lichenoid drug eruption; terbinafine.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antifungal Agents / adverse effects*
  • Drug Eruptions / etiology*
  • Drug Eruptions / pathology
  • Humans
  • Lichenoid Eruptions / chemically induced*
  • Lichenoid Eruptions / pathology
  • Male
  • Naphthalenes / adverse effects*
  • Skin / drug effects
  • Skin / pathology
  • Terbinafine
  • Tinea / drug therapy
  • Young Adult

Substances

  • Antifungal Agents
  • Naphthalenes
  • Terbinafine