Stressed out? Healing Tips for Newly Reprogrammed Neurons

Giorgia Quadrato; Aurora C Zhang; Paola Arlotta

doi:10.1016/j.stem.2016.02.008

Stressed out? Healing Tips for Newly Reprogrammed Neurons

Cell Stem Cell. 2016 Mar 3;18(3):297-9. doi: 10.1016/j.stem.2016.02.008.

Authors

Giorgia Quadrato¹, Aurora C Zhang¹, Paola Arlotta²

Affiliations

¹ Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA.
² Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA. Electronic address: [email protected].

PMID: 26942845
DOI: 10.1016/j.stem.2016.02.008

Abstract

How do astrocyte-derived neurons deal with the sudden loss of their glial identity? Exciting new findings from Gascón et al. (2016) single out metabolic conversion as a critical checkpoint for direct neuronal reprogramming.

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MeSH terms

Astrocytes
Neuroglia*
Neurons / metabolism*