Relationship between Daytime Sleepiness and Intrinsically Photosensitive Retinal Ganglion Cells in Glaucomatous Disease

Carolina P B Gracitelli; Gloria Liliana Duque-Chica; Ana Laura de Araújo Moura; Marina Roizenblatt; Balazs V Nagy; Geraldine Ragot de Melo; Paula Delegrego Borba; Sérgio H Teixeira; Sergio Tufik; Dora Fix Ventura; Augusto Paranhos Jr

doi:10.1155/2016/5317371

Relationship between Daytime Sleepiness and Intrinsically Photosensitive Retinal Ganglion Cells in Glaucomatous Disease

J Ophthalmol. 2016:2016:5317371. doi: 10.1155/2016/5317371. Epub 2016 Feb 3.

Affiliations

¹ Department of Ophthalmology, Federal University of São Paulo, Rua Botucatu, 821 Vila Clementino, 04023-062 São Paulo, SP, Brazil.
² Experimental Psychology Department, Institute of Psychology, University of São Paulo, São Paulo, SP, Brazil.
³ Department of Ophthalmology, Federal University of São Paulo, Rua Botucatu, 821 Vila Clementino, 04023-062 São Paulo, SP, Brazil; Experimental Psychology Department, Institute of Psychology, University of São Paulo, São Paulo, SP, Brazil.
⁴ Sleep Medicine Division, Psychobiology Department, Federal University of São Paulo, São Paulo, SP, Brazil.

Abstract

Patients with glaucoma showed to have higher daytime sleepiness measured by Epworth sleepiness scale. In addition, this symptom was associated with pupillary reflex and polysomnography parameters. These ipRGC functions might be impaired in patients with glaucoma, leading to worse quality of life.