[Effects of low-dose oral contraceptives on sugar metabolism]

Minerva Ginecol. 1989 Sep;41(9):441-4.
[Article in Italian]

Abstract

The effects on carbohydrate metabolism by four low-dose oral contraceptives were evaluated in four low-dose oral contraceptives were evaluated-66 young women randomly divided in four groups. In the various preparations there were a different dosage of estrogen (ethinylestradiol) together different doses and types of progestogen (desogestrel, gestodene, cyproterone acetate). After six months of treatment, in all groups a slight increase of glycemic and insulinemic responses during OGTT was observed; the significance was achieved with the preparation containing cyproterone acetate alone. Glycated hemoglobin did not change. Our results suggest that these new low-dose oral contraceptives induced negligible metabolic side effects.

Publication types

  • Clinical Trial
  • English Abstract
  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Adult
  • Blood Glucose / analysis
  • Carbohydrate Metabolism*
  • Contraceptives, Oral, Hormonal / administration & dosage
  • Contraceptives, Oral, Hormonal / pharmacology*
  • Female
  • Humans
  • Insulin / blood

Substances

  • Blood Glucose
  • Contraceptives, Oral, Hormonal
  • Insulin