RNA-sequencing analysis of core binding factor AML identifies recurrent ZBTB7A mutations and defines RUNX1-CBFA2T3 fusion signature

Blood. 2016 May 19;127(20):2498-501. doi: 10.1182/blood-2016-03-703868. Epub 2016 Mar 11.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Cohort Studies
  • Core Binding Factor Alpha 2 Subunit / genetics*
  • DNA-Binding Proteins / genetics*
  • Female
  • Humans
  • Leukemia, Myeloid, Acute / genetics*
  • Male
  • Middle Aged
  • Mutation*
  • Oncogene Proteins, Fusion / genetics*
  • RNA / genetics
  • Repressor Proteins / genetics*
  • Transcription Factors / genetics*
  • Transcriptome
  • Tumor Suppressor Proteins / genetics*
  • Young Adult

Substances

  • CBFA2T3 protein, human
  • Core Binding Factor Alpha 2 Subunit
  • DNA-Binding Proteins
  • Oncogene Proteins, Fusion
  • RUNX1 protein, human
  • Repressor Proteins
  • Transcription Factors
  • Tumor Suppressor Proteins
  • ZBTB7A protein, human
  • RNA