Abstract
Mastomys natalensis rodents are natural hosts for Lassa virus (LASV). Detection of LASV in 2 mitochondrial phylogroups of the rodent near the Niger and Benue Rivers in Nigeria underlines the potential for LASV emergence in fresh phylogroups of this rodent. A Mobala-like sequence was also detected in eastern Nigeria.
Keywords:
Lassa; Mastomys natalensis; Nigeria; West Africa; arenaviruses; hemorrhagic fever; lineages; phylogeography; phylogroups; rodents; viruses.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Cytochromes b / genetics
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DNA, Mitochondrial / genetics*
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Disease Reservoirs
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Genetic Variation
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Host-Pathogen Interactions
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Humans
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Lassa Fever / epidemiology
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Lassa Fever / transmission
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Lassa Fever / veterinary*
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Lassa Fever / virology
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Lassa virus / classification*
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Lassa virus / genetics
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Lassa virus / isolation & purification
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Mitochondria / chemistry
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Mitochondria / genetics
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Murinae / classification
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Murinae / genetics
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Murinae / virology*
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Nigeria / epidemiology
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Phylogeny*
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Phylogeography
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RNA, Viral / genetics*
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Rodent Diseases / epidemiology
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Rodent Diseases / virology
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Zoonoses
Substances
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DNA, Mitochondrial
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RNA, Viral
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Cytochromes b