Submillisievert CT using model-based iterative reconstruction with lung-specific setting: An initial phantom study

Eur Radiol. 2016 Dec;26(12):4457-4464. doi: 10.1007/s00330-016-4307-5. Epub 2016 Mar 17.

Abstract

Objective: To assess image quality of filtered back-projection (FBP) and model-based iterative reconstruction (MBIR) with a conventional setting and a new lung-specific setting on submillisievert CT.

Methods: A lung phantom with artificial nodules was scanned with 10 mA at 120 kVp and 80 kVp (0.14 mSv and 0.05 mSv, respectively); images were reconstructed using FBP and MBIR with conventional setting (MBIRStnd) and lung-specific settings (MBIRRP20/Tx and MBIRRP20). Three observers subjectively scored overall image quality and image findings on a 5-point scale (1 = worst, 5 = best) compared with reference standard images (50 mA-FBP at 120, 100, 80 kVp). Image noise was measured objectively.

Results: MBIRRP20/Tx performed significantly better than MBIRStnd for overall image quality in 80-kVp images (p < 0.01), blurring of the border between lung and chest wall in 120p-kVp images (p < 0.05) and the ventral area of 80-kVp images (p < 0.001), and clarity of small vessels in the ventral area of 80-kVp images (p = 0.037). At 120 kVp, 10 mA-MBIRRP20 and 10 mA-MBIRRP20/Tx showed similar performance to 50 mA-FBP. MBIRStnd was better for noise reduction. Except for blurring in 120 kVp-MBIRStnd, MBIRs performed better than FBP.

Conclusion: Although a conventional setting was advantageous in noise reduction, a lung-specific setting can provide more appropriate image quality, even on submillisievert CT.

Key points: • Lung-specific submillisievert 10 mA-MBIR CT setting has similar performance to 50 mA-FBP • The new lung-specific settings improve vessel clarity and blurring of borders • The new settings may provide more appropriate images than conventional settings.

Keywords: Image enhancement; Image processing; Lung; Multidetector computed tomography; Radiation dosage.

MeSH terms

  • Algorithms
  • Humans
  • Lung / diagnostic imaging*
  • Models, Theoretical
  • Phantoms, Imaging
  • Radiation Dosage
  • Radiographic Image Interpretation, Computer-Assisted / methods*
  • Tomography, X-Ray Computed / methods*