Acute arterial ischemia in a patient with polyarthritis

Reumatol Clin. 2017 Mar-Apr;13(2):110-112. doi: 10.1016/j.reuma.2016.01.002. Epub 2016 Mar 23.
[Article in English, Spanish]

Abstract

Cryoglobulins are immunoglobulins that precipitate at cold temperatures. Their presence can be related to a type of vasculitis referred to as cryoglobulinemia. This condition, especially mixed cryoglobulinemia, has been associated with viral infections like hepatitis C virus in 60%-90% of cases, but it has also been reported in relation to connective tissue diseases, usually resulting in a more severe course. We describe the case of a patient with seronegative polyarthritis who developed acute arterial ischemia in association with cryoglobulinemia, with a good response to rituximab therapy.

Keywords: Acute arterial ischemia; Crioglobulinemia; Cryoglobulinemia; Isquemia arterial aguda; Lupus eritematoso sistémico; Rituximab; Systemic lupus erythematosus.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Arterial Occlusive Diseases / diagnosis
  • Arterial Occlusive Diseases / etiology*
  • Arthritis / etiology*
  • Cryoglobulinemia / diagnosis
  • Cryoglobulinemia / etiology*
  • Female
  • Hand / blood supply*
  • Humans
  • Ischemia / diagnosis
  • Ischemia / etiology*
  • Lupus Erythematosus, Systemic / complications
  • Lupus Erythematosus, Systemic / diagnosis*
  • Peripheral Vascular Diseases / diagnosis
  • Peripheral Vascular Diseases / etiology*
  • Radial Artery