Abstract
Fifteen 1-(quinolizidinylalkyl)amino derivatives of thioxanthenone bearing different substituents on position 4 and 7 were prepared and tested in mice against lymphocytic leukemia P 388. These compounds were inactive or displayed only borderline activity (compounds 1, 10, 15).
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Antineoplastic Agents / chemical synthesis*
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Chemical Phenomena
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Chemistry
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Leukemia P388 / drug therapy*
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Mice
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Mice, Inbred Strains
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Quinolizines / chemical synthesis*
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Quinolizines / pharmacology
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Spectrophotometry, Infrared
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Spectrophotometry, Ultraviolet
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Thioxanthenes / chemical synthesis*
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Thioxanthenes / pharmacology
Substances
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Antineoplastic Agents
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Quinolizines
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Thioxanthenes