Intraoperative Transcranial Motor-Evoked Potentials Predict Motor Function Outcome in Intracerebral Hemorrhage Surgery

World Neurosurg. 2016 Jun:90:518-523. doi: 10.1016/j.wneu.2016.03.058. Epub 2016 Mar 26.

Abstract

Objective: Prediction of motor function after intracerebral hemorrhage (ICH) often poses a diagnostic challenge. This study was performed to investigate whether intraoperative monitoring of motor-evoked potentials (MEPs) could predict postoperative motor function recovery.

Methods: We reviewed 16 consecutive patients undergoing evacuation of supratentorial ICH with hemiplegia between June 2011 and October 2014. Patients were categorized according to the results of MEPs before and after evacuation of hematoma. The correlation between detection of MEPs and prognosis of motor function was analyzed.

Results: In 10 of 16 cases (62%), stable MEPs were detected before and after evacuation of hematoma, and postoperative motor function was improved in all cases, including 3 cases with severe preoperative motor impairment on manual muscle test (1-2). In 3 cases (19%) in which MEPs were not detected throughout the procedure, motor function was not improved. In the other 3 cases (19%), MEPs were not measured before evacuation of ICH but were detected after evacuation despite poor prognosis of motor function. The results of postevacuation MEPs were considered false-negative results. Predictions using pre-evacuation MEP results were completely consistent with prognosis for recovery, whereas MEPs obtained during and after evaluation were useful for monitoring.

Conclusions: Intraoperative MEPs may indicate preservation of pyramidal tracts, and pre-evacuation MEPs can predict motor function outcome after ICH surgery.

Keywords: Hemiparesis; Intracerebral hemorrhage; Motor function; Motor-evoked potential; Prediction; Prognosis.

MeSH terms

  • Aged
  • Brain Mapping / methods
  • Cerebral Hemorrhage / complications
  • Cerebral Hemorrhage / diagnosis*
  • Cerebral Hemorrhage / surgery*
  • Evoked Potentials, Motor*
  • Female
  • Humans
  • Intraoperative Neurophysiological Monitoring / methods*
  • Male
  • Movement Disorders / diagnosis*
  • Movement Disorders / etiology*
  • Movement Disorders / prevention & control
  • Neurosurgical Procedures / adverse effects
  • Outcome Assessment, Health Care / methods*
  • Reproducibility of Results
  • Retrospective Studies
  • Sensitivity and Specificity
  • Treatment Outcome