A novel mechanism of NPM1 cytoplasmic localization in acute myeloid leukemia: the recurrent gene fusion NPM1-HAUS1

Haematologica. 2016 Jul;101(7):e287-90. doi: 10.3324/haematol.2015.137364. Epub 2016 Apr 1.
No abstract available

Keywords: acute myeloid leukemia; gene fusion; nucleophosmin.

Publication types

  • Case Reports
  • Clinical Trial
  • Letter

MeSH terms

  • Aged
  • Cell Cycle Proteins* / genetics
  • Cell Cycle Proteins* / metabolism
  • Cytoplasm* / genetics
  • Cytoplasm* / metabolism
  • Cytoplasm* / pathology
  • Female
  • Humans
  • Leukemia, Myeloid, Acute* / genetics
  • Leukemia, Myeloid, Acute* / metabolism
  • Leukemia, Myeloid, Acute* / pathology
  • Male
  • Microtubule-Associated Proteins* / genetics
  • Microtubule-Associated Proteins* / metabolism
  • Middle Aged
  • Nuclear Proteins* / genetics
  • Nuclear Proteins* / metabolism
  • Nucleophosmin
  • Oncogene Proteins, Fusion* / genetics
  • Oncogene Proteins, Fusion* / metabolism

Substances

  • Cell Cycle Proteins
  • HAUS1 protein, human
  • Microtubule-Associated Proteins
  • NPM1 protein, human
  • Nuclear Proteins
  • Oncogene Proteins, Fusion
  • Nucleophosmin