Iron Deficiency Anemia: Problems in Diagnosis and Prevention at the Population Level

Sant-Rayn Pasricha; Hal Drakesmith

doi:10.1016/j.hoc.2015.11.003

Iron Deficiency Anemia: Problems in Diagnosis and Prevention at the Population Level

Hematol Oncol Clin North Am. 2016 Apr;30(2):309-25. doi: 10.1016/j.hoc.2015.11.003.

Authors

Sant-Rayn Pasricha¹, Hal Drakesmith²

Affiliations

¹ MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DS, UK. Electronic address: [email protected].
² MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DS, UK.

PMID: 27040956
DOI: 10.1016/j.hoc.2015.11.003

Abstract

Anemia is common among people living in low- and middle-income countries, and alleviation of the global burden of anemia is an essential global health target over the next decade. Estimates have attributed about half the cases of anemia worldwide to iron deficiency; a range of other causes probably make a similar overall contribution. Individuals living in low-income settings experience a simultaneous high burden of infection with inflammation and iron deficiency. At least in children, iron supplementation exacerbates the risk of infection in both malaria-endemic and nonendemic low-income countries, whereas iron deficiency is protective against clinical and severe malaria.

Keywords: Anemia; Children; Hepcidin; Infection; Iron; Malaria; Public health.

Publication types

Review

MeSH terms

Anemia, Iron-Deficiency / diagnosis*
Anemia, Iron-Deficiency / epidemiology
Anemia, Iron-Deficiency / etiology
Anemia, Iron-Deficiency / prevention & control*
Female
Global Health
Humans
Male
Pregnancy
Prevalence

Abstract

Publication types

MeSH terms

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