Acute Paracoccidioidomycosis Due to Paracoccidioides brasiliensis S1 Mimicking Hypereosinophilic Syndrome with Massive Splenomegaly: Diagnostic Challenge

Priscila Marques de Macedo; Luã Cardoso de Oliveira; Dayvison Francis Saraiva Freitas; Jaqueline Abel da Rocha; Andrea D'Ávila Freitas; Marcio Nucci; Rosely Maria Zancopé-Oliveira; Rodrigo Almeida-Paes; Antonio Carlos Francesconi do Valle

doi:10.1371/journal.pntd.0004487

Acute Paracoccidioidomycosis Due to Paracoccidioides brasiliensis S1 Mimicking Hypereosinophilic Syndrome with Massive Splenomegaly: Diagnostic Challenge

PLoS Negl Trop Dis. 2016 Apr 7;10(4):e0004487. doi: 10.1371/journal.pntd.0004487. eCollection 2016 Apr.

Authors

Priscila Marques de Macedo¹, Luã Cardoso de Oliveira², Dayvison Francis Saraiva Freitas¹, Jaqueline Abel da Rocha³, Andrea D'Ávila Freitas⁴, Marcio Nucci⁵, Rosely Maria Zancopé-Oliveira², Rodrigo Almeida-Paes², Antonio Carlos Francesconi do Valle¹

Affiliations

¹ Infectious Dermatology Clinical Research Laboratory, Evandro Chagas National Institute of Infectious Diseases, Fiocruz, Rio de Janeiro, Brazil.
² Mycology Laboratory, Evandro Chagas National Institute of Infectious Diseases, Fiocruz, Rio de Janeiro, Brazil.
³ Nosocomial Infection Surveillance and Control Program, Central Hospital of Military Police (HCPM), Rio de Janeiro, Brazil.
⁴ Department of Inpatient Health Care, Evandro Chagas National Institute of Infectious Diseases, Fiocruz, Rio de Janeiro, Brazil.
⁵ Department of Internal Medicine, Universidade Federal do Rio de Janeiro (HUCFF, UFRJ), Rio de Janeiro, Brazil.

No abstract available

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Diagnosis, Differential
Humans
Hypereosinophilic Syndrome / diagnosis*
Male
Paracoccidioides / genetics
Paracoccidioides / isolation & purification*
Paracoccidioidomycosis / diagnosis*
Paracoccidioidomycosis / drug therapy
Paracoccidioidomycosis / microbiology*
Splenectomy
Splenomegaly / etiology
Splenomegaly / microbiology*

Grants and funding

This work was supported in part by National Counsel of Technological and Scientifical Development [304976/2013-0 to RMZ-O] and Fundação de Amparo à Pesquisa do Rio de Janeiro [E-26/103.157/2011 to RMZ-O and 214303 to ACFV]. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.