(Dicer)phering roles of microRNA in platelets

Blood. 2016 Apr 7;127(14):1733-4. doi: 10.1182/blood-2016-01-694893.

Abstract

In this issue of Blood, Rowley et al report that noncoding RNAs precisely regulate the messenger RNA (mRNA) profile in platelets. Interfering in this process using genetically engineered mice affects hemostatic and thrombotic functions of platelets.

Publication types

  • Comment

MeSH terms

  • Animals
  • Blood Platelets / metabolism*
  • DEAD-box RNA Helicases / metabolism*
  • Humans
  • MicroRNAs / metabolism*
  • RNA Processing, Post-Transcriptional / physiology*
  • RNA, Messenger / metabolism*
  • Ribonuclease III / metabolism*

Substances

  • MicroRNAs
  • RNA, Messenger
  • Ribonuclease III
  • DEAD-box RNA Helicases