Xenopericardial self-made tube grafts in infectious vascular reconstructions: Preliminary results of an easy and ready to use surgical approach

Vascular. 2016 Dec;24(6):621-627. doi: 10.1177/1708538116644361. Epub 2016 Apr 7.

Abstract

Purpose: Infections are a major setback of vascular reconstruction and associated with considerable morbidity and mortality. We evaluated retrospectively our results with self-made bovine pericardial grafts in infected vessel revascularization versus standard graft material.

Basic methods: Retrospective analysis of 9 patients with bovine reconstruction and 10 patients with miscellaneous grafts (vein, homograft) for vascular infections.

Principal findings: Infection-free rate of the pericardial group was 100% in 17 months. For patients after reconstructions with miscellaneous grafts, the infection-free rate was 82% in 45 months. Overall in-hospital mortality was 10.5%. There were no in-hospital deaths in the pericardial group. Graft patency of the whole cohort was 100%. The median follow up was 11.74 months.

Conclusion: Self-made bovine pericardial tube grafts can be crafted to almost any size and adjusted to complex anatomic requirements. The use was feasible in various situations and was associated with good preliminary results concerning patency and reinfection.

Keywords: Vascular reconstruction; bovine pericardium; graft infection; self-made graft; xenopericard.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Allografts
  • Animals
  • Blood Vessel Prosthesis / adverse effects*
  • Blood Vessel Prosthesis Implantation / adverse effects*
  • Blood Vessel Prosthesis Implantation / instrumentation*
  • Blood Vessel Prosthesis Implantation / mortality
  • Cattle
  • Disease-Free Survival
  • Female
  • Heterografts
  • Hospital Mortality
  • Humans
  • Male
  • Middle Aged
  • Pericardium / transplantation*
  • Prosthesis Design
  • Prosthesis-Related Infections / microbiology
  • Prosthesis-Related Infections / mortality
  • Prosthesis-Related Infections / physiopathology
  • Prosthesis-Related Infections / surgery*
  • Recurrence
  • Reoperation
  • Retrospective Studies
  • Time Factors
  • Treatment Outcome
  • Vascular Patency
  • Veins / transplantation