A phase II randomized controlled trial of nicotinamide for skin cancer chemoprevention in renal transplant recipients

A C Chen; A J Martin; R A Dalziell; C A McKenzie; P M Lowe; J M Eris; R A Scolyer; H M Dhillon; J L Vardy; V A Bielski; G M Halliday; D L Damian

doi:10.1111/bjd.14662

A phase II randomized controlled trial of nicotinamide for skin cancer chemoprevention in renal transplant recipients

Br J Dermatol. 2016 Nov;175(5):1073-1075. doi: 10.1111/bjd.14662. Epub 2016 Aug 10.

Authors

A C Chen^{1

2}, A J Martin³, R A Dalziell¹, C A McKenzie⁴, P M Lowe^{2

5}, J M Eris^{2

6}, R A Scolyer^{2

4

7}, H M Dhillon⁸, J L Vardy^{8

9

10}, V A Bielski⁶, G M Halliday^{1

2}, D L Damian^{11

12

13}

Affiliations

¹ Dermatology and Bosch Institute, University of Sydney at Royal Prince Alfred Hospital, Camperdown, Australia.
² Central Clinical School, Sydney Medical School, University of Sydney, Sydney, Australia.
³ NHMRC Clinical Trials Centre, University of Sydney, Camperdown, Australia.
⁴ Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Sydney, Australia.
⁵ Department of Dermatology, Royal Prince Alfred Hospital, Sydney, Australia.
⁶ Renal Medicine, Royal Prince Alfred Hospital, Sydney, Australia.
⁷ Melanoma Institute Australia, Sydney, Australia.
⁸ Centre for Medical Psychology and Evidence-Based Decision-Making, University of Sydney, Sydney, Australia.
⁹ Sydney Medical School, Concord Clinical School, University of Sydney, Sydney, Australia.
¹⁰ Concord Repatriation General Hospital, Sydney, Australia.
¹¹ Dermatology and Bosch Institute, University of Sydney at Royal Prince Alfred Hospital, Camperdown, Australia. [email protected].
¹² Central Clinical School, Sydney Medical School, University of Sydney, Sydney, Australia. [email protected].
¹³ Melanoma Institute Australia, Sydney, Australia. [email protected].

PMID: 27061568
DOI: 10.1111/bjd.14662

No abstract available

Publication types

Clinical Trial, Phase II
Letter
Randomized Controlled Trial

MeSH terms

Administration, Oral
Adult
Aged
Anticarcinogenic Agents / therapeutic use*
Carcinoma, Squamous Cell / prevention & control*
Chemoprevention / methods
Double-Blind Method
Drug Administration Schedule
Female
Humans
Immunosuppression Therapy / adverse effects
Kidney Transplantation / adverse effects*
Male
Middle Aged
Niacinamide / administration & dosage*
Skin Neoplasms / prevention & control*
Transplant Recipients
Treatment Outcome
Vitamin B Complex / therapeutic use*

Substances

Anticarcinogenic Agents
Vitamin B Complex
Niacinamide