The journey for adolescents and young adults with chronic conditions transitioning to adult care with successful warfarin management

Thromb Res. 2016 May:141:183-8. doi: 10.1016/j.thromres.2016.03.019. Epub 2016 Mar 17.

Abstract

Health transition of youth from a child-centered care model to the adult model has been recognized to be of critical importance due to the increasing numbers of children now surviving chronic conditions. A formalized transition process is required adequately assess the AYA's readiness for transition and to move towards adult care. Indefinite warfarin therapy poses challenges as warfarin is a narrow therapeutic index drug that requires frequent monitoring and attentiveness to warfarin interactions and affects.

Objective: The objective of this study was to evaluate transition to adult care for AYAs requiring indefinite warfarin therapy within a structured self-management program.

Outcome measures: Results were compared between Phase 1 (enrollment to patient self-management) and Phase 2 (independent warfarin management) 6months following confirmation of transition to adult care. There was no statistical difference between outcome measures except INR testing frequency, and no adverse events.

Conclusions: This transition process resulted in successful transition as measured by TTR and other clinical end-points from pediatric to adult care. Implementing a formal transition process for young adults with chronic health conditions that considers patient preferences motivates and empowers them over time to develop autonomy with warfarin self-management, results in successful transition and warfarin management.

Keywords: Adolescent; Coumadin; Pediatrics; Point of care monitoring; Quality of life; Transition; Vitamin K antagonist; Warfarin; Warfarin self-management; Warfarin self-testing; Young adult.

MeSH terms

  • Adolescent
  • Adult
  • Anticoagulants / therapeutic use*
  • Child
  • Disease Management
  • Drug Monitoring
  • Female
  • Humans
  • International Normalized Ratio
  • Male
  • Point-of-Care Testing
  • Quality of Life
  • Self Administration*
  • Transition to Adult Care
  • Warfarin / therapeutic use*
  • Young Adult

Substances

  • Anticoagulants
  • Warfarin