Churg-Strauss syndrome associated with antiphospholipid antibodies in a patient with retinal vasculitis

Arch Soc Esp Oftalmol. 2016 Nov;91(11):547-550. doi: 10.1016/j.oftal.2016.03.003. Epub 2016 Apr 9.
[Article in English, Spanish]

Abstract

Case report: We present the case of a 69-year-old woman with unilateral retinal vasculitis. Investigations showed asthma, rhinosinusitis, nasal polyposis, peripheral blood eosinophilia, increased sedimentation rate, proteinuria, and antiphospholipid antibodies. Anti-neutrophil cytoplasmic antibodies (ANCA) were negative.

Discussion: Although her anti-neutrophil cytoplasmatic antibody (ANCA) status was negative, taking into account the other clinical and laboratory features, retinal vasculitis was thought to be an ocular manifestation of Churg-Strauss syndrome. Treatment was started with high-dose corticosteroids and anticoagulant therapy.

Keywords: Anti-neutrophil cytoplasmatic antibody; Anticuerpos antifosfolipídicos; Anticuerpos antineutrófilos citoplasmáticos; Antiphospholipid antibodies; Churg-Strauss syndrome; Oclusión venosa retiniana; Retinal vasculitis; Retinal vein occlusion; Síndrome de Churg-Strauss; Vasculitis retiniana.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antibodies, Antiphospholipid / blood*
  • Asthma / etiology
  • Churg-Strauss Syndrome / blood
  • Churg-Strauss Syndrome / complications*
  • Churg-Strauss Syndrome / drug therapy
  • Churg-Strauss Syndrome / immunology
  • Colitis, Ischemic / etiology
  • Eosinophilia / etiology
  • Female
  • Fluorescein Angiography
  • Humans
  • Ischemia / diagnostic imaging
  • Ischemia / etiology
  • Laser Coagulation
  • Macular Edema / etiology
  • Macular Edema / surgery
  • Neuritis / etiology
  • Retinal Hemorrhage / etiology
  • Retinal Hemorrhage / surgery
  • Retinal Vasculitis / diagnostic imaging
  • Retinal Vasculitis / etiology*

Substances

  • Antibodies, Antiphospholipid