Background: Doxorubicin is an antineoplastic agent frequently used in diverse cancer regimens. Cutaneous adverse effects have frequently been reported with its use. However, a flagellate-like dermatitis is not mentioned in the literature.
Objective: The investigators report a case of toxic erythema of chemotherapy with a flagellate pattern induced by doxorubicin.
Methods and results: A 75-year-old woman with endometrial cancer received doxorubicin as part of her treatment. After her third cycle, she presented a pruritic vesiculobullous eruption, with linear elements that left hyperpigmented streaks on follow-up. A biopsy was compatible with a drug eruption.
Conclusion: Doxorubicin is a well-known cause of toxic erythema of chemotherapy. As seen in this patient, the investigators suggest that it also be added to the list of causes of flagellate dermatosis.
Keywords: dermatology; doxorubicin; flagellate dermatitis; inflammatory dermatosis; toxic erythema of chemotherapy.
© The Author(s) 2016.